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Varicose Veins, Thread Veins, Spider Veins, PhotoDerm, Sclerotherapy, Surgery, Thrombosis
Varicose Veins, Thread Veins, Spider Veins, PhotoDerm, Sclerotherapy, Surgery, Thrombosis
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Foam Injections

Ultrasound Guided Foam Sclerotherapy

Recently several new techniques have been reported in the medical literature. The main aim of these is to avoid surgical removal of varicose veins. The idea is to avoid the need for general anaesthetic, incisions in the legs and a hospital operating theatre. One of the most promising of these is Ultrasound Guided Foam Sclerotherapy.

History

The use of injections to cure varicose veins dates back more than 100 years. In 1942 Orbach described a method of creating a foam or froth with the solution he injected. He found that this increased the efficacy of injection treatment by five times. This method was used by a small number of surgeons but never found a great following.

In 1992 Juan Cabrera, a surgeon from Granada in Spain, found that he could greatly enhance the effect of injection treatment by making a foam of very small bubbles, which he called 'microfoam'. He used ultrasound imaging to guide his injections into the main surface veins and found that he no longer needed surgical methods to treat his patients.

Over the last 15 years the use of foam injections has spread widely in France, Spain, Italy and Germany. It is now being enthusiastically taken up in several European countries, United States, South America, Australia and New Zealand. Experts in treating vein problems have used a number of different methods to create the foam that they inject but the result is the same: using a foam greatly increases the effect of the treatment without producing any additional side-effects.

Recently a pharmaceutical company, Provensis, has commenced development of a foam called 'Varisolve'. This is specifically intended to treat varicose veins. 'Varisolve' is currently only in use in clinical trials. The National Institute of Clinical Excellence has considered this treatment and published draft advice.

What is injected?

The solutions that are injected are exactly the same as those which are already used to treat varicose veins. These are mixed with air to create a mousse or foam consisting of very small bubbles. It has been shown that this is perfectly safe to inject into the veins. The air is rapidly absorbed from the veins leaving the solution to treat the veins.
Why does foam work?

When a solution is injected into a vein it is immediately diluted by the blood, reducing its efficacy. Foam pushes the blood out of the way and completely fills the vein: the foam is not diluted by the blood. In fact, far less solution has to be injected to obtain the same effect.

The treatment

Treatment is usually performed in a treatment room or ultrasound examination room, and not an operating theatre. The patient rests comfortably on a bed. Very little discomfort results from the injections so no sedation or anaesthetic is required.

In order to treat large varicose veins it is necessary to block the main vein feeding the varices. This could be done surgically, but with foam treatment all that is necessary is to put a needle into the main affected surface vein. This is the only part of the procedure which might cause discomfort and is usually performed with a small amount of local anaesthetic. The position of the needle is carefully monitored using ultrasound imaging so that it is in exactly the right place.

Next, the foam is injected whilst watching its progress using the ultrasound machine. Surprisingly, injecting the foam causes no discomfort, although the leg may ache slightly afterwards.

The varicose veins in the leg are checked to see if foam has entered these from the main surface vein where the injection was given. A few further injections are usually given through a tiny needle in order to make sure that all the varicose veins have been completely injected. The whole treatment usually takes no more than 20 - 30 minutes.

Finally a firm bandage is applied to the leg. The aim of this is to keep the veins compressed so that they do no fill with blood when the patient stands up. The bandage is usually worn for a week or two followed by an elastic compression stocking for a further week.

When the bandages are removed at the follow-up appointment it is usual to find that all the varicose veins have gone. Sometimes small lumps can be felt beneath the skin. The leg may be a little bruised, although this is usually fairly minor. Lumps present at this stage slowly resolve over several weeks. If any varicose veins have not been completely treated in the first session they are injected and the leg bandaged to complete removal of all veins.

If varicose veins are present in both legs it is standard practice to treat them on separate occasions about two weeks apart. This avoids having both legs bandaged at once.

Who is suitable for foam sclerotherapy?

Most patients with small or moderate size varicose veins can be treated in this way. Those patients with very extensive large varicose veins are usually best treated surgically to obtain a more rapid result. Some patients with large veins lying close to the skin are better treated surgically since brown discoloration of the skin over the treated vein may occur. If there has been previous surgery to the veins of the leg this does not cause any difficulty in using foam sclerotherapy. In fact, it is often far easier to treat recurrent varicose veins by foam injections than by more surgery. If varicose veins recur some years after initial treatment then it is straightforward to use the same method foam sclerotherapy again.

Who performs this treatment?

At present only a handful of surgeons in the UK are experienced in this treatment. It needs a specialist who is skilled at ultrasound imaging as well as injecting veins. By calling the BVI you can obtain an appointment with your nearest expert.

How well does ultrasound guided foam sclerotherapy work?

Several detailed clinical series have been published in the medical press. These suggest that 80 - 90% of saphenous veins (the main surface vein) are permanently occluded by this treatment when examined one or two years later using ultrasound imaging . This is similar to the success rate claimed for other new techniques such as VNUS Closure and Endovenous Laser Treatment (See: New Techniques). Surgery also has its failures and after two years further varicose veins may have appeared in about 10% of patients. Clinical trials are currently in progress which directly compare surgery and foam sclerotherapy.

Good points

Stripping of the vein is avoided and there is little or no discomfort after treatment.
There is much less bruising than following surgery.
There is no need for general anaesthetic, incisions in the leg, admission to hospital or an operating theatre.
Re-treatment for further varices is simple.

Much less expensive than surgical treatment - less than half the cost of surgery.

No time needed off work, except for the treatment sessions.

Bad points

The treatment produces mild discomfort in the leg which may last for 2 - 4 weeks. It also produces mild bruising which may last for several weeks following treatment. However, both of these features are usually seen following surgical treatment for varicose veins.
The final outcome may take a number months to evolve following treatment, and this is longer than would be taken following surgery.

Scientific publications and abstracts

Paper br Dr Cabrera (1.1MB)
Abstract from Venous Forum of the Royal Society of Medicine (0.1MB)
Abstract from Pacific Vascular Symposium (0.15MB)

Conclusions

  • Ultrasound guided foam sclerotherapy is a new method of treating varicose veins.
  • There is NO need for an operation under general anaesthetic.
  • The treatment only involves injections under local anaesthetic.
  • A treatment session is complete in 30 - 40 minutes.
  • The treatment is carefully monitored using ultrasound imaging.
  • A firm compression bandage must be worn for a week or two afterwards.
  • Mild discomfort and a little bruising often follow treatment. This is much less than following surgical treatment.
  • No time off work is needed, except to attend the clinic appointments.
  • The costs of treatment are much lower than for surgical methods.
  • Some small lumps may be felt in place of the veins after treatment. These resolve completely over several months.
  • Only a few specialists in the UK have experience with this technique. The BVI can put you in touch with the nearest one.
 
 
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